Pharamceutical Analysis Unit- 2 Semester -1 MCQs
1.Methyl orange is??
Pink in acidic medium, yellow in basic medium.
Yellow in acidic medium, pink in basic medium.
Colourless in acidic medium, pink in basic medium.
Pink in acidic medium, colourless in basic medium.
SOLUTION
Pink in acidic medium, yellow in basic medium
2.The function of quick lime in soda lime mixture is to?
Absorb moisture present in soda lime.
Increase the efficiency of soda lime.
Increase the pH of soda lime.
Take part in reaction with NaOH.
SOLUTION
Absorb moisture present in soda lime
3.What is the concentration of the sulphuric acid solution, if 100 ml of the solution is neutralised by 50 ml of 0.5 M Ba(OH)2 solution.
0.25 M
50 M
0.5 M
100 M
SOLUTION
0.25 M
4.How many percentage of acetic acid in oracet blue B
0.3% w/v
0.5 % w/v
0.2% w/v
0.1% w/v
SOLUTION
0.5 % w/v
5.In acid base titration at pH 6.8-8.4 which indicator are used
Bromocresol blue
Phenol red
Methyl orange
Methyl red
SOLUTION
Phenol red
6.Which of the following is a general property of base?
Taste Sour.
Turnlitums red.
Conduct electric current in solution.
Concentration of h3o is greater than concen. of oh.
SOLUTION
Conduct electric current in solution
7.Which one of the following will turn blue litmus red
Vinegar
Lime water
Baking soda solution
Washing soda solution
SOLUTION
Vinegar
8.Resonance Theory is?
The same in color of the same compound in acid and base medium is apparently due to difference in structure of two forms
The difference in color of the same compound in acid and base medium is apparently due to same in structure of two forms
The difference in color of the different compound in acid and base medium is apparently due to difference in structure of two forms
The difference in color of the same compound in acid and base medium is apparently due to same in structure of two forms
SOLUTION
The difference in color of the same compound in acid and base medium is apparently due to difference in structure of two forms
9.When titration occur between Weak acid and strong base which indicator are used
Thymol Blue
Phenolphthalein
A and B
None of the above
SOLUTION
A and B
10.If 30 ml of acid is neutralised by 15 ml of 0.2 N alkali, then the concentration of acid is
0.4 N
0.1 N
0.3 N
0.15 N
SOLUTION
0.3 N
11.pH of 7 is shown through a color of
Red
Blue
Green
Yellow
SOLUTION
Green
12.Which sentence is false about indicator?
Phenolphthalein give colourless solutions at pH 8.3-11.0 in acidic medium
Methyl red give red solutions at pH 4.2-6.6 in acidic medium
Methylorange give orange solutions at pH 3.1-4.4 in base medium
Methylred give red solutions at pH 4.2-6.6 in basic medium
Solution
Methylred give red solutions at pH 4.2-6.6 in basic medium
13.Which of the following is used as an indicator in the titration of a strong acid and a weak base
Phenolphthalein
Thymol blue
Fluorescein
Methyl orange
SOLUTION
Methyl orange
14.What is the molarity of the solution of barium hydroxide, if 35 ml of 0.1 M HCl is used in the titration of 25 ml of the barium hydroxide solution
0.35
0.07
0.28
0.14
SOLUTION
0.07
15.The chemical formula of caustic potash is
NaOH
Ca(OH)2
NH4OH
KOH
SOLUTION
KOH
16.Which of the following does not form an acidic salt
Phosphoric acid
Carbonic acid
Hydrochloric acid
Sulphuric acid
SOLUTION
Carbonic acid
17.A solution of known concentration is the definition of a
Buffer solution
Standard solution
Neutral solutions
Standard solutions
SOLUTION
Standard solution
18.The difference of molecules of water in gypsum and PoP is
5/2
2b
3/2
½
SOLUTION
3/2
19.Which indicator give magenta in basic medium
Quinaldine red
1-Naphthol benzenein
C.Oracet blue B
D.Thymol blue
SOLUTION
Quinaldine red
20.Q-
Which of the following titrations will have the equivalence point at a pH more than 8
HCl and NH3
CH3COOH and NH3
HCl and NaOH
CH3COOH and NaOH
SOLUTION
CH3COOH and NaOH
21.Which of the following salts has no water of crystallization
Blue vitriol
Washing soda
Baking soda
Gypsum
SOLUTION
Baking soda
22.Which is example of Protophilic solvent
H2SO4
KOH
HAC
Benzene
SOLUTION
KOH
23.Find the concentration of HCl, if 10 ml of 0.5 M Ca(OH)2 is required to titrate 50 ml of HCl
5 M
1/10 M
10 M
1/5 M
SOLUTION
1/5 M
24.The ideal indicator for the titration of strong acid and weak base should have pH range between
5-8
4-6
8-10
7-8
SOLUTION
4-6
25.Atropine methonitrate is Assay by which method
Acid base titration
Non aqueous titration
Karl fischer titration
NMR
SOLUTION
Non aqueous titration
26.The Ph of a solution of HCL is 4. This shows that the molarity of the solution is
4.0M
0.4M
0.0001M
0.001M
SOLUTION
4.0M
27.Which one of the following is acidic
Lemon juice
Tomatoes
Milk
All
SOLUTION
All
28.When titration occur between Weak base and strong acid which indicator are used
Methyl orange
Methyl red
A and B
None of the above
SOLUTION
A and B
29.Assay of boric acid is done by
Direct titration (Alkalimetry)
Direct titration (Acidimetry)
A and B
None of the above
SOLUTION
Direct titration (Alkalimetry)
30.Which is example of aprotic solvent
H2SO4
KOH
HAC
Benzene
SOLUTION
Benzene
31.Which is example of Protogenicsolvents
H2SO4
KOH
HAC
Benzene
SOLUTION
H2SO4
32.Which compound is Titration are carried out by non aqueousTitration
Organic acids
Organic bases
A and B
None of the above
SOLUTION
A and B
33.Which is correct sequence of assay of aspirin
Aspirin+ 2-3 drops of phenolphthalin +NaOH solutions +ethanol
Aspirin+NaOH solutions +ethanol +2-3 drops of phenolphthalin
Aspirin +ethanol +2-3 drops of phenolphthalin + NaOH solutions
Aspirin+NaOH solutions +ethanol +2-3 drops of phenolphthalein
SOLUTION
Aspirin +ethanol +2-3 drops of phenolphthalin + NaOH solutions
34.Which indicator give yellowcolour in basic medium
a. Crystal violet
B.1-Naphthol benzenein
C.Oracet blue B
D.Thymol blue
SOLUTION
D.Thymol blue
35.Methyl red is give red colour at which pH
1.2-3.5
4.2-6.6
7.8-8.9
9.8-10.2
SOLUTION
4.2-6.6
36.Diazepam is Assay by which method
Acid base titration
B.Non aqueous titration
Karl fischer titration
NMR
SOLUTION
B.Non aqueous titration
37.Which one of the following will turn red litmus blue
Vinegar
Baking soda solution
Lemon juice
Soft drinks
SOLUTION
Baking soda solution
38.Which of the following is used as an indicator in the titration of a weak acid and a strong base.
Bromothymol blue (6 to 7.5)
Methyl orange (3 to 4)
Methyl red (5 to 6)
Phenolphthalein (8 to 9.6)
SOLUTION
Phenolphthalein (8 to 9.6)
39.The nature of calcium phosphate is present in tooth enamel is
Basic
Amphoteric
Acidic
Neutral
SOLUTION
Basic
40.Which is not a disadvantage of Non – aqueous Titration??
Volatile solvent can polute environment.
Solvent are expensive..
Indicator must be prepare in non-aqueous medium.
Organic acids which is of comparable strength to water can be titrated easily in non-aqueous solvent.
SOLUTION
Organic acids which is of comparable strength to water can be titrated easily in non-aqueous solvent
41.Which of the following is a buffer solution
H2SO4 + CuSO4
CH3COOH + CH3COONH4
NaCl + NaOH
CH3COONa + CH3COOH
SOLUTION
CH3COONa + CH3COOH
42.Lime water is
CaO
Ca(OH)2
CaCO3
CaCI2
SOLUTION
Ca(OH)2
43.Which sentence is false about Henderson-Hasselbalch equation
It is used to determine pKa value of solutions.
pH of solutions containing comparable and appreciable conc. of a conjugate acid-base pair to ratio of their concentrations.
It is used to calculate valency of molecule.
pH = pka + log [conjugated base]/[conjugated acid].
SOLUTION
It is used to calculate valency of molecule
44.Which of the following is responsible for the acidic pH of normal rainwater
CO2
NO2
SO2
NH3
SOLUTION
CO2
45.Which is correct sequence of assay of barbiturates??
Barbiturates + methanol +water +indicator + NaOH solution.
Barbiturates + indicator + methanol +water + NaOH solution.
Barbiturates + NaOH solutions +water +methanol.
None of the above.
SOLUTION
Barbiturates + methanol +water +indicator + NaOH solution
46.How many w/v of methanol present in Quinaldine red
0.3
B.0.2
C.0.1
D.0.4
SOLUTION
C.0.1
47.Which one of the following indicators would be most suitable for this titration??
Any acid/base indicator is suitable
Phenolphthalein (pKa = 9.6)
Cresol red (pKa = 8.3)
Methyl red (pKa = 5.1)
SOLUTION
Methyl red (pKa = 5.1)
48.Pilocarpine nitrate is Assay by which method?
Acid base titration
Non aqueous titration
Karl fischer titration
NMR
SOLUTION
Non aqueous titration
49.Nicotinamide is Assay by which method
Acid base titration
Non aqueous titration
Karl fischer titration
NMR
SOLUTION
Non aqueous titration
50. A difference between strong and weak acid is?
Presence and absence of halogen ions.
Negative and positive pH.
Complete and partial ionisation.
Proton donation and electron acceptance.
SOLUTION
Complete and partial ionisation