BP203 T. Biochemistry Hand Written Notes
BP203 T. Biochemistry Hand Written Notes drx gyan
Scope: Biochemistry deals with a complete understanding of the molecular levels of the
chemical process associated with living cells. The scope of the subject is providing
biochemical facts and the principles to understand the metabolism of nutrient molecules in
physiological and pathological conditions. It is also emphasizing the genetic organization
of the mammalian genome and hetero & autocatalytic functions of DNA.
Biomolecules
Introduction, classification, chemical nature and biological role of
carbohydrate, lipids, nucleic acids, amino acids and proteins. Bioenergetics
Concept of free energy, endergonic and exergonic reaction, Relationship
between free energy, enthalpy and entropy; Redox potential.
Energy rich compounds; classification; biological significances of ATP
and cyclic.
Bioenergetics
Concept of free energy, endergonic and exergonic reaction, Relationship
between free energy, enthalpy and entropy; Redox potential.
Energy rich compounds; classification; biological significances of ATP
and cyclic AMP.
Lipid metabolism
β-Oxidation of saturated fatty acid (Palmitic acid)
Formation and utilization of ketone bodies; ketoacidosis
De novo synthesis of fatty acids (Palmitic acid)
Biological significance of cholesterol and conversion of cholesterol into
bile acids, steroid hormone and vitamin D
Disorders of lipid metabolism: Hypercholesterolemia, atherosclerosis,
fatty liver and obesity. Amino acid metabolism
General reactions of amino acid metabolism: Transamination,
deamination & decarboxylation, urea cycle and its disorders
Catabolism of phenylalanine and tyrosine and their metabolic disorders
(Phenyketonuria, Albinism, alkeptonuria, tyrosinemia)
Synthesis and significance of biological substances; 5-HT, melatonin,
dopamine, noradrenaline, adrenaline
Catabolism of heme; hyperbilirubinemia and jaundice
Biochemistry-unit-3rd-lipid-metabolism
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